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            VAV1抗原,鳥苷酸轉換因子VAV1抗原

            更新時間:2024-12-04點擊次數(shù):71

            Recombinant human VAV1   

            Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .  

            濃度:1mg/ ml

            來源:Recombinant Human

            純度:≥95% SDS-PAGE

            表達系統(tǒng):Escherichia coli

            標簽:His tag N-Terminus

            蛋白長度:Full length protein

            內毒素水平:<1.000 Eu/µg

            純化方法:HPLC

            應用:SDS-PAGE,Western blot,ELISA

            Biological activity,immunology research

            保存:-20℃

            保質期:1年

            This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 



            產品名稱:Rabbit Anti-VAV1  antibody

            Rabbit Anti-VAV1  

            別名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .     

            來源:Rabbit

            克隆類型:Polyclonal

            濃度:1mg/ml

            亞型:IgG

            應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應:Human (predicted: Mouse,Rat,Pig,Cow,Horse)

            理論分子量:98kDa

            免疫原:KLH conjugated synthetic peptide derived from human VAV1

            保存:-20
            保質期:1

             

            單克隆抗體

            產品名稱:Anti-VAV1 antibody

            Mouse Anti-VAV1 

            別名:Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN .  

            來源:Mouse

            克隆類型:Monoclonal

            濃度:1mg/ml

            亞型:IgG

            應用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

            反應: Human

            理論分子量:98kDa

            免疫原:KLH conjugated synthetic peptide derived from human VAV1

            保存:-20
            保質期:1

            This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. 


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