技術(shù)文章
TECHNICAL ARTICLESRecombinant human WAVE 1 protein
Protein WAVE-1; Protein WAVE1; SCAR1; Similar to a plant extensin like protein; Verprolin homology domain containing protein 1; Verprolin homology domain-containing protein 1; WAS protein family, member 1; Wasf1; WASF1_HUMAN; WASL; WASP family 1; WASP family protein member 1; WAVE; WAVE1; Wiskott Aldrich syndrome protein family member 1; Wiskott-Aldrich syndrome protein family member 1.
濃度:1mg/ ml
來(lái)源:Recombinant Human
純度:≥95% SDS-PAGE
表達(dá)系統(tǒng):Escherichia coli
標(biāo)簽:His tag
蛋白長(zhǎng)度:Full length protein
內(nèi)毒素水平:<1.000 Eu/µg
純化方法:HPLC
應(yīng)用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
保存:-20℃
保質(zhì)期:1年
WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases. The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac. They mediate Actin polymerization by cooperating with the Arp2/3 complex, thereby promoting the formation of Actin filaments. WAVE1, which is also designated SCAR (suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes. WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility.
產(chǎn)品名稱:Rabbit Anti-WAVE 1 protein antibody
Rabbit Anti-WAVE 1 protein
別名:Protein WAVE-1; Protein WAVE1; SCAR1; Similar to a plant extensin like protein; Verprolin homology domain containing protein 1; Verprolin homology domain-containing protein 1; WAS protein family, member 1; Wasf1; WASF1_HUMAN; WASL; WASP family 1; WASP family protein member 1; WAVE; WAVE1; Wiskott Aldrich syndrome protein family member 1; Wiskott-Aldrich syndrome protein family member 1.
來(lái)源:Rabbit
克隆類型:Polyclonal
濃度:1mg/ml
亞型:IgG
反應(yīng):Human (predicted: Mouse,Rat,Rabbit,Cow,Dog,Horse)
應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
理論分子量:61kDa
免疫原:KLH conjugated synthetic peptide derived from human WAVE 1 protein
保存:-20℃
保質(zhì)期:1年
產(chǎn)品名稱:Anti-WAVE 1 protein antibody
Mouse Anti-WAVE 1 protein
別名:Protein WAVE-1; Protein WAVE1; SCAR1; Similar to a plant extensin like protein; Verprolin homology domain containing protein 1; Verprolin homology domain-containing protein 1; WAS protein family, member 1; Wasf1; WASF1_HUMAN; WASL; WASP family 1; WASP family protein member 1; WAVE; WAVE1; Wiskott Aldrich syndrome protein family member 1; Wiskott-Aldrich syndrome protein family member 1.
來(lái)源:Mouse
克隆類型:Monoclonal
濃度:1mg/ml
亞型:IgG
反應(yīng):Human
應(yīng)用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500
IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
反應(yīng): Human
理論分子量:61kDa
免疫原:KLH conjugated synthetic peptide derived from human WAVE 1 protein
保存:-20℃
保質(zhì)期:1年
WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in Actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the Actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating Actin reorganization downstream of the Rho family of small GTPases. The protein homologs WAVE1 and WAVE2 regulate membrane ruffling by inducing the formation of Actin filament clusters in response to GTP binding and by activating Rac. They mediate Actin polymerization by cooperating with the Arp2/3 complex, thereby promoting the formation of Actin filaments. WAVE1, which is also designated SCAR (suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed, with the expression highest in peripheral blood leukocytes. WAVE3 forms a multiprotein complex that links receptor kinases with Actin and plays a role in the transduction of signals involving changes in cell shape, function or motility.
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