技術文章
TECHNICAL ARTICLESRecombinant human Zyxin
ESP2; HED2; ZYX; Zyxin2.
濃度:1mg/ ml
來源:Recombinant Human
純度:≥90% SDS-PAGE
表達系統(tǒng):Mammalian
標簽:His tag N-Terminus
蛋白長度:Full length protein
內毒素水平:<1.000 Eu/µg
純化方法:HPLC
應用:SDS-PAGE,Western blot,ELISA
Biological activity,immunology research
保存:-20℃
保質期:1年
Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
單克隆抗體
產品名稱:Anti-Zyxin antibody
Mouse Anti-Zyxin
別名:ESP2; HED2; ZYX; Zyxin2.
來源:Mouse
克隆類型:Monoclonal
濃度:1mg/ml
亞型:IgG
應用: WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IF=1:50-1:200,IP=1:20-1:50
反應: Human
理論分子量:61kDa
免疫原:KLH conjugated synthetic peptide derived from human Zyxin
保存:-20℃
保質期:1年
多克隆抗體
產品名稱:Rabbit Anti-Zyxin antibody
Rabbit Anti-Zyxin
別名:ESP2; HED2; ZYX; Zyxin2.
來源:Rabbit
克隆類型:Polyclonal
濃度:1mg/ml
亞型:IgG
應用: WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IF=1:50-1:200,IP=1:20-1:50
反應: (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse)
理論分子量:61kDa
免疫原:KLH conjugated synthetic peptide derived from human Zyxin
保存:-20℃
保質期:1年
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
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