技術(shù)文章
TECHNICAL ARTICLES產(chǎn)品名稱:Anti-Lubricin antibody
Rabbit Anti-Lubricin
別名:Superficial zone proteoglycan; articular superficial zone protein; bG174L6.2; CACP; camptodactyly arthropathy coxa vara pericarditis syndrome gene; FLJ32635; HAPO; Jacobs camptodactyly-arthropathy-pericarditis syndrome gene; JCAP; megakaryocyte stimulating factor; MSF; PRG 4; PRG4; proteoglycan 4; Proteoglycan4; Superficial zone proteoglycan; SZP; PRG4_HUMAN.
來源:Rabbit
克隆類型:polyclonal
濃度:1mg/ml
亞型:IgG
應(yīng)用: WB=1:500-1000 ELISA=1:500-1000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
反應(yīng): Human,Mouse, Rat
免疫原:KLH conjugated synthetic peptide derived from human Lubricin
Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.
保存:-20℃
保質(zhì)期:1年
上海允麥,供應(yīng)Lubricin抗體對應(yīng)的抗原
Lubricin抗原
Lubricin antigen
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